STREPTOCOCCUS PNEUMONIAE PRODUCING HYBRID POLYSEROTYPE CAPSULAR POLYSACCHARIDE AND HYBRID POLYSEROTYPE CAPSULAR POLYSACCHARIDE PRODUCED THEREFROM

摘要

The present invention relates to Streptococcus pneumoniae producing hybrid polyserotype capsular polysaccharide and the hybrid polyserotype capsular polysaccharide produced from the Streptococcus. More specifically, the Streptococcus pneumoniae prepared by transfecting a vector comprising a repeat unit polymerase wzy19A gene of serotype 19A capsular polysaccharide into Streptococcus pneumoniae serotype 19F effectively produces a hybrid polyserotype capsular polysaccharide of 19A and 19F. Therefore, the Streptococcus pneumoniae and the hybrid polyserotype capsular polysaccharide produced therefrom can be useful as a vaccine for Streptococcus pneumonia.