MULTIVALENT cx-GAL NEOGLYCOCONJUGATE FOR IMMUNOLOGICAL STUDIES IN CHAGAS DISEASE

摘要

Synthetic oligosaccharides and their glycoconjugates are useful tools for the diagnostic of several diseases and for immunological studies. On the other hand, the introduction of multivalency by incorporation of an antigenic structure into a multiarm scaffold increases the density of the epitopes, similarly to the presentation that glycoconjugates often have in biological systems. This increment favors the binding specificity to serum antibodies.