首页> 外国专利> COMPOSITION AND ITS PREPARATION PROCESS USING ANTIGEN CONJUGATED TO ENZYMATIC ACTIVITY FOR IMMUNOLOGICAL DIAGNOSIS AND CHAGAS' DISEASE IMMUNOLOGICAL DIAGNOSIS KITS, FOR INDIVIDUAL AND EPIDEMIOLOGICAL APPLICATION, BASED ON THAT COMPOSITION

COMPOSITION AND ITS PREPARATION PROCESS USING ANTIGEN CONJUGATED TO ENZYMATIC ACTIVITY FOR IMMUNOLOGICAL DIAGNOSIS AND CHAGAS' DISEASE IMMUNOLOGICAL DIAGNOSIS KITS, FOR INDIVIDUAL AND EPIDEMIOLOGICAL APPLICATION, BASED ON THAT COMPOSITION

机译:基于该成分的结合酶活性的抗原的组合物及其制备方法,用于免疫诊断和查加斯病的免疫诊断试剂盒,基于该成分在个体和流行病学中的应用

摘要

we described the use of antigen combined with an enzymatic activity for detection of immune complexes prepared from mixtures containing antigens and antigenic conjugates, which allows the detection of low titre antibodies through the development of a color reaction.the method is based on the specificity of the antibodies and can be used in the diagnosis of infectious diseases, provided that it is used with the appropriate antigen.the requirements for the diagnosis of chagas' disease using recombinant antigens of trypanosoma cruzi as described in the patent application pct / ro / 91 (brazilian submission number 9001479 work of 30 march 1990)and are indicated in the diagnosis of chagas' disease in immunologically using either elisa or antigen immobilized on solid supports such as pyroxylin, nylon, polyvinyl chloride, polycarbonate, and the polyallomu00e8re.
机译:我们描述了结合酶活性使用抗原来检测由包含抗原和抗原结合物的混合物制备的免疫复合物的方法,该方法可通过显色反应的发展来检测低滴度的抗体。抗体,只要与适当的抗原一起使用即可用于感染性疾病的诊断。专利申请pct // ro / 91中所述的使用克氏锥虫的重组抗原诊断南美锥虫病的要求(1990年3月30日,巴西提交的9001479号工作),并通过免疫或固定在固体支持物(如吡咯啉,尼龙,聚氯乙烯,聚碳酸酯和聚allomé)上的酶联免疫吸附法在查加斯病的诊断中得到了指示。

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