Department of Cancer Research;
Fujian Medical College;
Fuzhou 350004;
Department of Cancer Research;
Fujian Medical College;
Fuzhou 350004he present paper reports 11 cases of light chain disease (LCD) sequently found in several citles over Fujian province;
Immunological classification of this group of LCD ww as follows: six of me cases belonged to type λ;
four of them were type κ;
and another one was a double LCD. We found that LCD was common in Fujlan only next to multiple myeloma (MM) of IgG class and accounted for 20% of the total 55 MM cases found in recent yean.It to well known that In matt patients of LCD M protein or Bence Jones proteinemia (BJPemia) to not detectable by conventional electro-phoresis. Our studies show that by making serum protein along with urinary BJP electrophoresis on the same one gel plate the sltuation can be greatly Improved It not only favour* the recognition of smail and faint band or bands of free light chain in serum;
but also provides a repid and sensitive way;
i. e.;
immunofixation;
to directly detect urinary light chain on the gel plate Immediately after electrophresis has been run.;
Multiple; myeloma; Light; chain; disease; Immunological; diagnosis.;