SEMISYNTHESIS OF COMPLEX-TYPE BIANTENNARY OLIGOSACCHARIDES CONTAINING LACTOSAMINE REPEATING UNITS FROM A BIANTENNARY OLIGOSACCHARIDE ISOLATED FROM A NATURAL SOURCE

摘要

Poly-N-acetylIactosamine (Poly-LacNAc) structures on nonreducing terminals of oligosaccharides is one of the major structural features observed on complex-type oligosaccharides. This poly-LacNAc structures play important roles in many biological processes such as cell-cell adhesions; however, a detail of relationships between poly-LacNAc structures and chemical properties/biological activities of glycoproteins is still not clear.