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Step-wise potential development across the lipid bilayer under external electric fields

机译:在外部电场下脂质双层的潜在开发

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Pore formation across the bilayers under external electric field is an important phenomenon, which has numerous applications in biology and bio-engineering fields. However, it is not a ubiquitous event under all field applications. To initiate a pore in the bilayer a particular threshold electric field is required. The electric field alters the intrinsic potential distribution across the bilayer as we as it enhances total potential drop across the bilayer, which causes the pore formation. The intrinsic potential profile has a maximum peak value, which is 0.8 V and it gets enhanced under application of external field, 0.43 V/nm. The peak value becomes 1.4 V when a pore appears in the bilayer and it continues to evolve as along as the external electric field remains switched on.
机译:外部电场下双层穿过双层的孔隙形成是一种重要现象,其在生物学和生物工程领域具有许多应用。但是,它在所有现场应用程序下都不是无处不在的事件。为了在双层中引发孔,需要特定的阈值电场。电场在双层穿过双层的内在电位分布,因为我们可以增强穿过双层的总潜力,这导致孔形成。内在电位轮廓具有最大峰值,其为0.8V,在外部场的应用下,它得到增强,0.43 v / nm。当孔隙出现在双层时,峰值变为1.4V,并且随着外部电场仍然接通开启,它继续发展。

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