From my initial entry into the field of diagnostic virology in 1982 until the early 2000's, the information concerning canine infectious respiratory disease (CIRD) or acute respiratory disease of canines (ARDC) was relatively static. There were several viruses associated with respiratory infections [canine distemper virus (CDV), canine adenovirus-2 (CAV-2), canine parainfluenza virus (CPIV)], but the main concern seemed to be focused on Bordetella bonchiseptica with or without various mycoplasma sp.The core canine vaccine panel essentially eliminated CDV and CAV-2 from the respiratory disease picture in immunized dogs. Vaccines for CPIV and B. bronchiseptica were added to try and reduce morbidity, but there continued to be instances where fully vaccinated dogs still experienced clinically significant respiratory disease. The opportunities for transmission of infectious agents among dog are substantial when one considers the animal rescue agencies, the breed rescue groups that move animals over substantial distances, commercial kennels, "doggie" day-care facilities, dog parks, and canine competitions of numerous varieties. Better definition of CIRD was clearly needed.
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