BIOACTIVITY EVALUATION OF SOL-GEL DERIVED MAGNESIUM-SUBSTITTUED FLUORAPATITE NANOCRYSTALLINE POWDERS

摘要

In this study, Mg-doped fluorapatite (Mg-FA) nanopowders were prepared through a sol-gel technique and characterized. Designated degree of Mg2+ ions incorporation into the apatite structure was indicated by the x value in the general formula of (Ca_(10?x)Mg_x (PO_4)_6F_2), where x=0, 0.25, 0.5, 0.75, and 1. XRD, AAS, FTIR and TEM techniques were utilized to characterize the synthesized nanopowders. In vitro bioactivity of the powders was evaluated in simulated body fluid. Powders had a crystallite size less than 100 nm. It was concluded that Mg-substitution could alter bioactivity and dissolution behaviour of Mg-FA. These two parameters were proportional to magnesium content of the powders.