Preparation and Aggregate Formation of O-Hydroxypropyl-N-Laurel Acyl Chitosan Ramification

摘要

A new kind of amphiphilic derivatives of chitosan, O-hydroxypropyl-N-laurel acyl chitosan(O-HP-N-LACHS) ramification were synthesized. The chemical structures of the chitosan derivatives were characterized by FTIR, ~1(HNMR). The surface and aggregate properties were studied by means of surface tension and fluorescence measurements. Results showed that O-hydroxypropyl-N-laurel acyl chitosan can concentrate on the surface to decrease the surface tension and can associate with hydrophobic chains to form aggregates in the solution. The abilities to decrease the surface tension and to form aggregates were promoted by increasing the DS of hydrophobic group.