Simultaneous determination of four immunosuppressants in whole blood - A fast method on a Shimadzu tandem LCMS-8030 mass analyser

摘要

Quantitative Assessment of immunosuppressant drug levels is, though extremely important to patients needs and sufficient organ survival in transplantation medicine, a challenging part of clinical laboratory procedure. Although there have been many approaches to simplify HPLC-MS by immunoassay methods it is still the most reliable method and gold standard procedure in modern clinical monitoring of immuno -suppressant therapy.