Metabolomics Profiling of G-protein-signaling Mutant Strains of Stagonospora nodorum by Hybrid Quadrupole Time-of-Flight Mass Spectrometry

摘要

Accurate mass with fast MS and MS/MS acquisition speeds of the TripleTOF~(TM) 5600 System has resolved thousands of peaks and generated structural information for metabolite identification. Preliminary statistical analysis differentiates the fungal strains and the metabolites contributing to differences between the strains are now being linked to the observed phenotypic effects of the mutations.