ANIDULAFUNGIN AND ITS PRIMARY BIOTRANSFORMATION PRODUCT - CHALLENGES IN AN LC-MS/MS BIOANALYTICAL ASSAY

机译：Anidulafungin及其主要生物转化产品 - LC-MS / MS生物分析测定中的挑战

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With no need to increase the low sample volume required for analysis or the linear response range, a rugged, accurate, precise and reproducible method was validated in 2009 and is presently used for analysis of Anidulafungin in plasma samples from several clinical studies.

机译：无需增加分析或线性响应范围所需的低样品体积，2009年验证了粗糙，准确，精确和可重复的方法，目前用于分析来自几种临床研究的血浆样本中的血管腺异常。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2010年||共1页
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Tanja Alebic-Kolbah; Michael Modesitt;
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中图分类 TB994.5-53;
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专利

1. Anidulafungin - Challenges in development and validation of an LC-MS/MS bioanalytical method validated for regulated clinical studies [J] . Alebic-Kolbah T., Modesitt M.S. Analytical and bioanalytical chemistry . 2012,第6a7期

机译：Anidulafungin-在经过合法临床研究验证的LC-MS / MS生物分析方法的开发和验证中面临的挑战
2. Anidulafungin - Challenges in development and validation of an LC-MS/MS bioanalytical method validated for regulated clinical studies [J] . Alebic-Kolbah T., Modesitt M.S. Analytical and bioanalytical chemistry . 2012,第6a7期

机译：Anidulafungin-在经过合法临床研究验证的LC-MS / MS生物分析方法的开发和验证中面临的挑战
3. Anidulafungin—challenges in development and validation of an LC-MS/MS bioanalytical method validated for regulated clinical studies [J] . Tanja Alebic-Kolbah, Michael S. Modesitt Analytical and Bioanalytical Chemistry . 2012,第6a7期

机译：Anidulafungin-在经过合法临床研究验证的LC-MS / MS生物分析方法的开发和验证中所面临的挑战
4. ANIDULAFUNGIN AND ITS PRIMARY BIOTRANSFORMATION PRODUCT - CHALLENGES IN AN LC-MS/MS BIOANALYTICAL ASSAY [C] . Tanja Alebic-Kolbah, Michael Modesitt American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：Anidulafungin及其主要生物转化产品 - LC-MS / MS生物分析测定中的挑战
5. Multiparametric LC-MS method development for a bioanalytical study of plant (phospho)proteomes. [D] . De Vijlder, Thomas. 2012

机译：多参数LC-MS方法开发用于植物（磷酸）蛋白质组的生物分析研究。
6. An LC-MS/MS Bioanalytical Assay for the Determination of Gilteritinib in Rat Plasma and Application to a Drug–Drug Interaction Study [O] . Qiong Wang, Zhe Chen, Dingwen Chen, 2020

机译：LC-MS / MS生物分析测定用于测定大鼠血浆中的Gilteritinib和应用于药物 - 药物相互作用研究
7. Bioanalytical LC-MS/MS method for Determination and comparison of Selexipag Assay in various Biological materials and its Application to Pharmacokinetics Studies in Rat plasma [O] . 2020

机译：生物分析LC-MS / MS / MS方法，用于测定和比较各种生物材料中的Selexipag测定及其对大鼠药代动力学研究的应用

ANIDULAFUNGIN AND ITS PRIMARY BIOTRANSFORMATION PRODUCT - CHALLENGES IN AN LC-MS/MS BIOANALYTICAL ASSAY

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