LASER-ABLATION RAPID EVAPORATIVE IONIZATION MASS SPECTROMETRY (LA-REIMS) FOR LIPIDOMICS ANALYSIS OF LIVING CHO CELLS DIRECTLY FROM THE CELL CULTURE

摘要

Lipidomics analysis of living cells is still a difficult task, mainly because of the low abundance lipids that demand the use of time-consuming lipid extraction methods. In the present study we report the application of LA-REIMS directly in the cell culture, in ambient environment.