ASSIGNMENT OF LINKAGE, ANOMERIC CONFIGURATION, AND BRANCH LOCATION OF OLIGOSACCHARIDES VIA A LOGICALLY DERIVED MS~n APPROACH

摘要

Carbohydrates (or glycan) play influential roles in cellular recognition processes and many other biological processes. However, the structural determination of oligosaccharides remains an obstacle and constitutes a bottleneck in carbohydrate research. An approach for de novo structural determination of linear and branched oligosaccharides based on logically derived procedure of tandem mass spectrometry was demonstrate.