DEVELOPMENT OF A NEW METHOD FOR THE IDENTIFICATION OF FOLLICLE STIMULATING HORMONE (FSH) GLYCOFORMS INVOLVED HUMAN FERTILITY

摘要

Follicle-stimulating hormone (FSH) plays a key role in the proliferation and development of ovarian granulosa cells in women and spermatogenesis in men [1-3]. The glycosylation of FSH is extremely important since it has a significant influence on its biological activity. The quantitative determination of FSH at the various stages of the menstrual cycle is fundamental, for this reason, it is important to develop new methodologies that can lead to the simple and sensitive determination of FSH.