Microfluidic electrochemical cell with MS detection as tool for the study of the biotransformation of perfumery compounds

摘要

Chemicals interacting with living systems undergo to numerous transformations due to their participation to the complex network of biochemical reactions occurring in the organisms (metabolism). Biotransformation and bioaccumulation of xenobiotics are usually assessed by in-vivo assays however these methods are expensive, time consuming and raise ethical issues concerning the use of animal testing.