TISSUE IDENTIFICATION BY RAPID EVAPORATIVE IONIZATION MASS SPECTROMETRY (REIMS) BASED ON FRAGMENTATION PROFILE OF GLYCEROPHOSPHOLIPIDS

摘要

The presented data clearly demonstrates that REIMS has the potential of distinguishing different tissues based on the MS/MS spectra of only one precursor ion. Our findings suggest that the MS peaks contain several different phospholipid species, possibly from different classes. Since the relative contribution of isomeric phospholipids to a specific exact m/z value peak varies between different tissues, we have an additional information for the identification of different tissue types.