Development of a Sensitive and Specific LC-MS/MS Method for Rapid Diagnosis of Niemann-Pick C Disease

机译：开发敏感和特异性LC-MS / MS方法，用于快速诊断Niemann-Pick C病

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A rapid LC/MS/MS method has been developed for the determination of Bile Acid B in DBS. The assay exhibited a high degree of sensitivity, precision, and accuracy. Analysis of DBS from 4992 controls, 134 NPC carriers, and 68 NPC subjects provided diagnostic sensitivity of 100% and specificity of 100%.

机译：已经开发了一种快速的LC / MS / MS方法，用于测定DBS中的胆汁酸B.该测定表现出高度灵敏度，精度和准确性。 4992对照的DB分析，134个NPC载体和68个NPC受试者提供了100％和100％特异性的诊断敏感性。

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《ASMS Conference on Mass Spectrometry and Allied Topics》|2016年|1CD|共1页
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Rohini Sidhu; Xuntian Jiang; Sarah Gale; Dave Scherrer; Jean E. Schaffer; Daniel S. Ory;
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中图分类 TB994.5-53;
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1. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma. [J] . Jiang X, Sidhu R, Porter FD, Journal of Lipid Research . 2011,第7期

机译：一种灵敏，特异的LC-MS / MS方法，可从人血浆中快速诊断Niemann-Pick C1疾病。
2. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [J] . Xuntian Jiang, Rohini Sidhu, Forbes D. Porter, Journal of Lipid Research . 2011,第7期

机译：一种灵敏而特异性的LC-MS / MS方法，可从人血浆中快速诊断Niemann-Pick C1疾病
3. Determination of 7-ketocholesterol in plasma by lc-ms for rapid diagnosis of acid smase-deficient niemann-pick disease [J] . LinN., ZhangH., QiuW., Journal of Lipid Research . 2014,第2期

机译：液相色谱-质谱法测定血浆中的7-酮胆固醇，用于快速诊断胃酸缺乏症的尼尔曼-皮克病
4. Development of a Sensitive and Specific LC-MS/MS Method for Rapid Diagnosis of Niemann-Pick C Disease [C] . Rohini Sidhu, Xuntian Jiang, Sarah Gale, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：开发敏感和特异性LC-MS / MS方法，用于快速诊断Niemann-Pick C病
5. Development of Methods for the Analysis of Human Protamine Via 2D LC-MS/MS [D] . Samuel, Jacob Matthew 2018

机译：通过2D LC-MS / MS分析人鱼精蛋白的方法开发
6. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [O] . Xuntian Jiang, Rohini Sidhu, Forbes D. Porter, 2011

机译：一种灵敏且特异性的LC-MS / MS方法可从人血浆中快速诊断Niemann-Pick C1疾病
7. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma. [O] . Jiang, X, Sidhu, R, Porter, FD, 2011

机译：一种灵敏且特异的LC-MS / MS方法，可从人血浆中快速诊断Niemann-Pick C1疾病。

Development of a Sensitive and Specific LC-MS/MS Method for Rapid Diagnosis of Niemann-Pick C Disease

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