Dry Ion Localization Locomotion (DRILL) Interface Using Vortex Flow Hydrodynamics for Enhanced Sensitivity of Electrospray Ionization Mass Spectrometry

摘要

1. CFD shows that DRILL's vorticial flow can be established to separate droplets based on size. i. Initial experiments indicate need for better control of velocity & electric fields to minimize droplet losses due to wall impact 2. For largest observed droplets, desolvation occurs in ～60 ms. Realistic desolvation time will be smaller due to Coulombic repulsion & presence of volatile solvents