Gastric cancer (GC) is one of the most common cancers worldwide. Prognosis of cancer patients can dramatically be improved if gastric tumors are detected at early stage. Thus, a reliable and convenient screening method of GC is in a critical need. The biological samples such as serum or plasma are less invasive and have been used for clinical diagnosis. For stomach cancer diagnosis, gastric juice analysis is a good compromise because it is relatively easy to obtain gastric juice samples from patients by performing endoscopic checkups. Based on the improvement of mass spectrometry techniques, the peptidomic analysis is recently developed to a more convenient tool for biomarker discovery and disease diagnosis.
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