BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent MannerOpen

Hiroyuki Yamamoto; Yoshiyuki Watanabe; Ritsuko Oikawa; Ryo Morita; Yoshihito Yoshida; Tadateru Maehata; Hiroshi Yasuda; Fumio Itoh

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BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent MannerOpen

机译：使用胃洗液DNA或胃液外泌体DNA进行BARHL2甲基化是一种独立于幽门螺杆菌的早期检测胃癌的有用标志物

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Objectives:The main purpose of this study was to develop a methylation analysis pipeline by using gastric wash-derived DNA and/or gastric juice-derived exosomal DNA (exoDNA), and to evaluate its suitability for the early detection of gastric cancer (GC) in clinical settings.

机译：目的：本研究的主要目的是使用胃洗液衍生的DNA和/或胃液衍生的外泌体DNA（exoDNA）开发甲基化分析流程，并评估其在早期检测胃癌（GC）中的适用性。在临床环境中。

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《Clinical and Translational Gastroenterology》 |2016年第7期|共11页
作者
Hiroyuki Yamamoto; Yoshiyuki Watanabe; Ritsuko Oikawa; Ryo Morita; Yoshihito Yoshida; Tadateru Maehata; Hiroshi Yasuda; Fumio Itoh;
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中图分类内科学;
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专利

1. Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients. [J] . Muretto P, Ruzzo A, Pizzagalli F, Annals of oncology: official journal of the European Society for Medical Oncology . 2008,第3期

机译：弥漫性胃癌患者胃液中DNA的E-钙粘蛋白基因（CDH1）启动子高甲基化的胃内膜胶囊评估。
2. Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients [J] . P. Muretto1 A. Ruzzo2 F. Pizzagalli2 F. Graziano3 P. Maltese2 C. Zingaretti4 E. Berselli5 N. Donnarumma1 and M. Magnani2 Annals of Oncology . 2008,第3期

机译：弥漫性胃癌患者胃液DNA中E-钙粘蛋白基因（CDH1）启动子高甲基化的胃内膜胶囊评估
3. Somatic DNA Hypomethylation in H. pylori-Associated High-Risk Gastritis and Gastric Cancer: Enhanced Somatic Hypomethylation Associates with Advanced Stage CancerOpen [J] . Andreas Leodolter, Sergio Alonso, Beatriz González, Clinical and Translational Gastroenterology . 2015,第4期

机译：幽门螺杆菌相关的高风险胃炎和胃癌中的体细胞DNA甲基化不足：增强的体细胞甲基化不足与晚期癌症的关系
4. DNA methylation markers as predictors of initiation and progression of gastric carcinomas [C] . Liu ZJ1, Gao YH1, Zhang J1, International Gastric Cancer Congress . 2011

机译：DNA甲基化标志物作为胃癌的启动和进展的预测因子
5. Kinetics of Gastric Juice Diffusion to Solid Food During Digestion. [D] . Widjaja, Jessica Maria. 2010

机译：消化过程中胃液向固体食物扩散的动力学。
6. BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA isa Useful Marker For Early Detection of Gastric Cancer in an H.pylori-Independent Manner [O] . Hiroyuki Yamamoto, Yoshiyuki Watanabe, Ritsuko Oikawa, 2016

机译：使用胃洗液DNA或胃液外泌体DNA进行BARHL2甲基化早期发现胃癌的有用标记独立于幽门的方式
7. Detection of DNA methylation of gastric juice-derived exosomes in gastric cancer [O] . Hiroyuki Yamamoto 2014

机译：检测胃癌中胃液衍生外泌体DNA甲基化的检测

BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent MannerOpen

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