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DIFFUSION CONTROLLED, WATER-POWERED MICROACTUATOR FOR BIOMEDICAL AND MICROFLUIDIC APPLICATIONS

机译:扩散控制,用于生物医学和微流体应用的水源微致动器

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Current and advanced microfluidic and implantable biomedical devices present an increasing need for controlled mechanical actuation at the micro-scale, without the use of batteries or external power. Implantable applications such as drug delivery microdevices require long term, battery free operation to perform their operation over the course of many months or years. In this paper, we present a micro-electro-mechanical systems (MEMS) microactuator which is water-powered and does not require any external power or control for its operation. Furthermore, we have demonstrated that by controlling the diffusion of water through a lithographically defined semipermeable membrane, we can control the rate of this mechanical actuation. The microactuator uses a water-swellable polymer as the working agent and a thin membrane of PDMS (polydimethylsiloxane) as the semi-permeable membrane to allow selective diffusion of water into the actuator. The swelling of the polymer upon contact with water and the resulting pressure generated is used as the actuation mechanism. Self-powered microactuators that use this technology can be important for many microfluidic and biomedical applications such as pulsatile drug delivery.
机译:电流和先进的微流体和可植入的生物医学装置在没有使用电池或外部电力的情况下,越来越需要对微尺度的受控机械致动。植入应用如药物送货微生物需要长期,电池免费操作在数月或数年内进行操作。在本文中,我们介绍了一种微电路系统(MEMS)微致动器,其是水供电的,并且不需要任何外部电源或控制的操作。此外,我们已经证明,通过通过光刻定义的半透膜控制水的扩散,我们可以控制这种机械致动的速率。微致催光剂使用可水溶胀的聚合物作为加工剂和作为半透膜的PDMS(聚二甲基硅氧烷)的薄膜,以允许水的选择性地扩散到致动器中。将聚合物与水接触时的溶胀和产生的所得压力用作致动机构。使用该技术的自动微耦合器对于许多微流体和生物医学应用(如脉动药物递送)都很重要。

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