首页> 外文会议>International Conference on Nanochannels, Microchannels and Minichannels; 20070618-20; Puebla(MX) >DIFFUSION CONTROLLED, WATER-POWERED MICROACTUATOR FOR BIOMEDICAL AND MICROFLUIDIC APPLICATIONS
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DIFFUSION CONTROLLED, WATER-POWERED MICROACTUATOR FOR BIOMEDICAL AND MICROFLUIDIC APPLICATIONS

机译:用于生物医学和微流体应用的扩散控制的水力微驱动器

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摘要

Current and advanced microfluidic and implantable biomedical devices present an increasing need for controlled mechanical actuation at the micro-scale, without the use of batteries or external power. Implantable applications such as drug delivery microdevices require long term, battery free operation to perform their operation over the course of many months or years. In this paper, we present a micro-electro-mechanical systems (MEMS) microactuator which is water-powered and does not require any external power or control for its operation. Furthermore, we have demonstrated that by controlling the diffusion of water through a lithographically defined semi-permeable membrane, we can control the rate of this mechanical actuation. The microactuator uses a water-swellable polymer as the working agent and a thin membrane of PDMS (polydimethylsiloxane) as the semi-permeable membrane to allow selective diffusion of water into the actuator. The swelling of the polymer upon contact with water and the resulting pressure generated is used as the actuation mechanism. Self-powered microactuators that use this technology can be important for many microfluidic and biomedical applications such as pulsatile drug delivery.
机译:当前和先进的微流体和可植入生物医学设备对在不使用电池或外部电源的情况下对在微观规模上进行受控机械致动的需求日益增长。诸如药物输送微设备之类的可植入应用需要长期无电池操作才能在数月或数年的时间内执行其操作。在本文中,我们介绍了一种微机电系统(MEMS)微执行器,该微执行器是水驱动的,不需要任何外部电源或控制其操作。此外,我们已经证明,通过控制水通过光刻定义的半透膜的扩散,我们可以控制这种机械驱动的速度。微致动器使用水溶胀性聚合物作为工作剂,并使用PDMS薄膜(聚二甲基硅氧烷)作为半透膜,以允许水选择性扩散到致动器中。与水接触时聚合物的溶胀和所产生的压力被用作致动机构。使用这种技术的自供电微执行器对于许多微流控和生物医学应用(例如搏动性药物输送)可能非常重要。

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