New Palladium-Catalyzed Processes for the Synthesis of Selectively Substituted Aromatics

摘要

Alkylaromatic palladacycles, formed in situ by reaction of palladium acetate with a strained and rigid cycloolefin such as norbornene and an ortho-substituted aryl iodide, allow the selective arylation of the aromatic ring by a second molecule of aryl iodide with subsequent norbornene expulsion. Coupling the resulting complex with appropriate reagents liberates the organic product thus regenerating the catalyst.