The possibility of preparing ophthalmic drug delivery systems using supercritical antisolvent technology was evaluated. Eudragit RS 100 and RL 100 were used as drug carriers and acetazolamide was the model drug processed. SAS experiments were performed at different operational conditions, and different formulations of polymer/drug were prepared. Experiments were performed using a liquid solution of the polymer + solute in acetone. The particles obtained were analysed by SEM and the particle size was determined.
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