Chronic Hepatitis is an etiologic diverse and morphologically variable condition characterized by mixed inflammatory cell infiltrates. Plasma cells, lymphocytes and macrophages predominate with a lesser number of neutrophils. The etiology of this chronic inflammatory condition is generally never determined. Etiologies associated chronic hepatitis include hepatic copper accumulation, drug-induced hepatitis specifically primidone and phenobarbital and infectious agents such as leptospirosis and infectious canine hepatitis. Other potential etiologies include alpha-antitrypsin (AAT) deficiency and autoimmune liver disease.
展开▼