Elementary Study on Producing Pharmaceutical Fungi with New Solid Fermentation Engineering

摘要

As a new research field of modern biology technology, the new solid fermentation engineering has a huge potentiality in the development of medicinal materials and utilization of biologic resources. In this paper, a study on producing three pharmaceutical fungi (Ganoder-ma lucidum Karst, Polystictus vesicolor (L.) Fr. , Grifola frondosa(Fr.) S. F. Gray) with herb residues as raw materials was made under the guide of new solid fermentation engineering, and the mam bioactive components (fungal polysaccharide, water-soluable protein, triter-pense)in medicinal fungal substance were measured and analysed. The results showed that as follows: firstly, there was a close relation among mycelium growth , the content of bioactive components(polysaccharide, water-soluable protein, ganoderic acid) and mycelium meba-tolism in fermentation process, but the changes were not completely synchronous ; secondly, ganoderic acid produced in fermentation process was less than that in fruitbody in both kind and content, so it was deduced that their producing ganoderic acid mechanism was probably different; thirdly, it was an effective approach to obtain fungal polysaccharide by solid fermentation with herb residues as raw materials.