Peptides of 4-methyl-pseudoproline derived from alpha-methylserine:synthesis approach and conformational aspects

摘要

As it has been reported by Mutter and coworkers [1],serine-and threonine-derived oxazolidine,and cysteine-derived thiazolidine derivatives,denoted as pseudoproline (PHIPro),exert a pronounced effect upon backbone conformation due to their structural similarity to proline itself.