Functionalized cyclodextrin-calix4arene host molecules for detection of organic analytes

摘要

Monofunctionalizedβ-Cyclodextrins were coupled to calix[4]arene derivatives bearing different fluorophores to give fluorescent cyclodextrin-calix[4]arene couples. The cyclodextrin-calix[4]arene couple 1 was investigated as a sensing molecule forthe detection of several organic analytes in aqueous solution. Inclusion of a guest into the fluorescent sensing molecule leads to a decrease in fluorescence intensity. Compound 1 shows selectivity for organic analytes of a certain length. The fluorescent sensing molecules 2-6 were synthesized in order to investigate the influence of the different parts of the molecules on the sensing properties.