DARWIIZER-a computer based method for peptide and peptidomimetics design

摘要

Due to the metabolic instability of peptides,the design of modified isofunctional peptidomimetics is an adequate approach toward their application in pharmacology.DARWINIZER is a computer-based tool for the de novo design of modified peptide structures.DARWINIZER is an extension of the PepHarvester and SME algorithm including non-canonical amino acids.