Antifungal Indole and Pyrrolidine-24-Dione Derivative Peptidomimetic Lead Design Based on In Silico Study of Bioactive Peptide Families

摘要

BackgroundThe rise of opportunistic fungal infections highlights the need for development of new antimicrobial agents. Antimicrobial Peptides (AMPs) and Antifungal Peptides (AFPs) are among the agents with minimal resistance being developed against them, therefore they can be used as structural templates for design of new antimicrobial agents.