Coacervation and CD and FT-IR spectroscopic studies of elastin-derived polypentapeptide and its analogs

摘要

Elastin imparts elasticity to elastic tissues such as arterial walls,lungs,ligaments,and skin.In vivo,tropoelastin,a precursor ofinsoluble elastin,self-associates with appropriate alignment in extracellular spaces,followed by cross-linking to form elastin.The self-association of tropoelastin moleculesis the most significant step in the process of elastin biosynthesis,termed coacervation in vitro.