Raman Spectroscopy As A Potential Rapid Screening Tool For Venous Thromboembolism

摘要

Each year in Europe, deaths stemming from Venous Thromboembolic (VTE) disorders (Deep Vein Thrombosis (DVT) and/or Pulmonary Embolism (PE)) more than double the total number of mortalities from breast cancer, prostate cancer, HIV/ AIDS and road traffic accidents combined.' Venography and pulmonary angiography are the gold standard methods to diagnose DVT and PE respectively — but they are invasive, costly and not universally available. Alternative non-invasive techniques, such as compression ultrasonography (CUS), ventilation-perfusion (V/Q), lung scintigraphy or spiral Computed Tomography also have limitations in terms of availability, cost and effectiveness.