PROLIFERATIVE NECROTIZING PNEUMONIA (PNP) IS A RESULT OF COINFECTION WITH PORCINE REPRODUCTIVE AND RESPIRATORY DISEASE VIRUS (PRRSV) AND PORCINE CIRCOVIRUS TYPE 2 (PCV2)

摘要

In 1991 a new disease in swine emerged in Germany - the proliferative necrotizing pneumonia, a disease similar to that previously described in Canada in 1990. First a atypical strain of Influenza A / swine / Saint Hyacinthe / 150 / 90 was mentioned tobe responsible for the new type of pneumonia. However PRRSV could be detected in nearly every lung with this specific type of histological lesions. Coincidentally PNP like pneumonia could first be recognized during the first outbreaks of Porcine reproductive and respiratory syndrome late in the 1980s and early 1990s in North American and Western European pig production. Whereas further pathogens, that had been known in 1991 were excluded to be the causative agent(s) by differential diagnosis, PRRSV was a promising candidate to be involved in that type of pneumonia.