Intestinal Uptake and Metabolism of Threonine: Nutritional Impact

摘要

Intestinal metabolism of dietary essential amino acids and its potential impact on their availability for whole-body growth has been the focus of many investigators' research over several decades. One of the major questions was concerned with the discrepancy between the disappearance of dietary essential amino acids from the small intestinal lumen and appearance in the portal circulation despite the fact that most commonly fed proteins are almost completely digestible. The earlier pioneering studieswith adult pigs made clear that the disappearance of essential amino acids from the lumen of the small intestine overestimates their availability to peripheral tissues of the host (Reratetal., 1988; 1992).