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Ultrasensitive biosensing based on plasmonic nanostructures

机译:基于等离子体纳米结构的超灵敏生物传感

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摘要

Hafnium-doped zinc oxide (HZO) has been recently demonstrated to be implemented as a transparent conductingoxide (TCO) material in photovoltaic applications but its plasmonic properties are left untouched. In this work, wesystematically investigate the plasmonic properties of gold nanoparticle (Au NP) arrays on thin HZO film, for differentratios of Hf dopants to Zinc oxide (ZnO) film. A localized surface plasmon resonant (LSPR) mode and two Braggmodes (due to the coupling of plasmon modes inside the film to array periodicity) are observed in the proposedstructure. Resonant excitation of these modes produces large field enhancement at the surface of the NPs as well asAu NP/HZO film interface and was observed with FDTD simulations. The optimized plasmonic structure will befabricated on quartz crystal microbalance (QCM) using laser interference lithography, based on the plasmonicresonant position and the SERS (surface enhanced Raman scattering) intensity, and it will be integrated to amicrofluidic device in the configuration of the lab-on-a-chip concept for biosensing applications.
机译:demonstrated掺杂的氧化锌(HZO)最近被证明可作为透明导电材料实现 光伏应用中使用的氧化物(TCO)材料,但其等离子体性能仍保持不变。在这项工作中,我们 系统地研究了HZO薄膜上金纳米粒子(Au NP)阵列的等离激元性质, Hf掺杂剂与氧化锌(ZnO)膜的比率局域表面等离子体共振(LSPR)模式和两个布拉格 提出的模式(由于薄膜内部的等离激元模式耦合到阵列周期性) 结构体。这些模式的共振激发会在NP的表面以及 Au NP / HZO薄膜界面,并通过FDTD模拟观察到。优化的等离子体结构将是 基于等离子体的激光干涉光刻技术在石英微天平(QCM)上制造 共振位置和SERS(表面增强拉曼散射)强度,并将其整合到 芯片实验室概念配置中的微流控设备,用于生物传感应用。

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