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The Effect of Depth on Fabrication of Nanopore using One-step Focused Ion Beam Milling for DNA Sequencing Application

机译:深度对一步聚焦离子束铣削制备DNA纳米孔的影响

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We report the effect of depth on fabrication of nanopore on silicon substrate by utilizing one-step focused ion beam (FIB) milling. The conical shaped of nanopores were successfully fabricated by optimizing the milling parameters of FIB system. The milling depth, base diameter and tip diameter of the resulting nanopores were characterized using field emission scanning electron microscope (FESEM). The minimum diameter of the conical shaped nanopore was found to be 66.51 nm. Moreover, when aspect ratio is less than unity, the redeposited material will land on the tip of the nanopores and adhere at the sidewall for high aspect ratio. This result will be beneficial towards the new generation of nanopore-based DNA sequencing.
机译:我们报告深度对利用单步聚焦离子束(FIB)铣削在硅基板上制造纳米孔的影响。通过优化FIB系统的铣削参数,成功制造出圆锥形的纳米孔。使用场发射扫描电子显微镜(FESEM)表征所得纳米孔的研磨深度,基径和尖端直径。发现圆锥形纳米孔的最小直径为66.51nm。而且,当长宽比小于1时,再沉积的材料将落在纳米孔的尖端上并粘附在侧壁上以获得高长宽比。该结果将对新一代基于纳米孔的DNA测序是有益的。

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