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Robot for MRI-guided Prostate Cancer Focal Laser Ablation

机译:用于MRI引导的前列腺癌局灶性激光消融的机器人

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Prostate cancer is the most common cancer among males, leading to approximately 27,000 deaths in the United States [1]. Focal laser ablation (FLA) has been shown to be a promising approach for prostate cancer treatment with the advantage of efficiently ablating the cancer cells while inflicting less damage on the surrounding tissues. In current FLA procedures, a rigid template - with holes spacing of 5mm - guides the FLA catheter to the target position. Drawbacks of the conventional approach for catheter targeting are 1) limited degrees of freedom (DoF) and 2) a low insertion resolution. In addition, the targeting capability of the rigid template is compromised when the pubic arch or nerve bundles intersect the catheter trajectory. We hypothesized that a compact design of an MRI-conditional robot with two active planar DoFs, one passive rotation DoF, and remote catheter insertion capacities could enhance the clinical workflow required for MRI-guided FLA prostate procedures.
机译:前列腺癌是男性中最常见的癌症,在美国约有27,000人死亡[1]。焦点激光烧蚀(FLA)已被证明是前列腺癌治疗的有希望的方法,其优点是有效地烧蚀癌细胞,同时对周围组织的损害较少。在当前的FLA程序中,一个刚性模板 - 具有5mm的孔间距 - 将FLA导管引导到目标位置。导管靶向的常规方法的缺点是1)限量自由度(DOF)和2)较低的插入分辨率。另外,当耻骨拱或神经束与导管轨迹相交时,刚性模板的靶向能力受到损害。我们假设具有两个有源平面DOF的MRI条件机器人的紧凑设计,一种被动旋转DOF和遥控导管插入能力可以增强MRI引导的FLA前列腺手术所需的临床工作流程。

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