Scanning Point Terahertz Source Microscope and Terahertz Microfluidic Chip for Biological Applications

摘要

We have developed an apertureless terahertz (THz) near-field microscope and a nonlinear optical crystal-based THz microfluidic chip for highly sensitive and high spatial resolution THz analysis of biological samples. Using these systems, we have succeeded in observing a clear THz image of a breast cancer tissue with a resolution of micrometer scale and in detecting solutes of attomole scale in a less than 100 pL volume of the solution.