The plasma protein fractions research by Raman spectroscopy method

摘要

This work is dedicated to the analysis of plasma proteins concentration using Raman spectroscopy setup. The obtained Raman spectra showed significant variation of intensities of certain spectral bands 940, 1005, 1330, 1450 and 1650 cm-1 for different protein fractions and concentrations. Partial least squares regression analysis was used for determination of correlation coefficients. We have shown that proposed method represents the structure and biochemical composition of albumin and immunoglobulins A and G.