Modulation of Macrophage Phenotype via Phagocytosis of Drug-Loaded Microparticles

摘要

These data suggest that intracellularly loading monocytes with Dex microparticles via phagocytosis could be a unique methodology to selectively modulate macrophage phenotype over time. This strategy would allow therapeutic administration of macrophages for the treatment of a number of inflammatory disease and disorders.