Collagen and Muscle Fibrous Tissue as a Contrast Mechanism in the THz region

摘要

We imaged a thin paraffin embedded sample with a terahertz time domain spectroscopy (THz-TDS) system. The sample was prepared from the laboratory guinea pigs after 7 weeks recovery from a brain surgery. The surgical wound and the surrounding normal skin tissue showed a clear contrast in the terahertz band despite of the sub-wavelength thickness of the sample. The comparison between the terahertz images and the stained histological images suggests that the contrast comes from the collagen-rich wound and the muscle fibrous tissue. This work demonstrates a potential contrast mechanism in terahertz tissue imaging.