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The Therapeutic Effect of Fetuin-A on the Calcified State of Smooth Muscle Cells

机译:Fetuin-A对平滑肌细胞钙化状态的治疗作用

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摘要

Fetuin-A successfully showed potential therapeutic effect for calcified vessels by effectively reducing calcium content in SMCs. Results warrant further research using high fetuin concentrations under calcifying conditions to maximize the effects of the protein as a therapy for vascular calcification. The next step in the process is to formulate a uremic in vitro model observe and manipulate the effects of fetuin in sites of calcification conditions to determine whether this therapy is effective.
机译:Fetuin-A通过有效降低SMC中的钙含量,成功地显示了对钙化血管的潜在治疗作用。结果值得进一步研究,在钙化条件下使用高胎球蛋白浓度以最大化蛋白质的作用,作为血管钙化的治疗方法。该过程的下一步是建立尿毒症体外模型,观察和操纵胎球蛋白在钙化条件部位的作用,以确定这种疗法是否有效。

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