DIFFERENTIATION METHOD TO SMOOTH MUSCLE CELL OF MESENCHYMAL STEM CELL, PRODUCTION METHOD OF SMOOTH MUSCLE IMPLANT, AND SMOOTH MUSCLE IMPLANT

摘要

PROBLEM TO BE SOLVED: To obtain a smooth muscle cell of a sufficient quantity while reducing a patient burden.SOLUTION: A differentiation method of a mesenchymal stem cell to a smooth muscle cell which includes a culturing step S4 that cultures by a condition that makes a mesenchymal stem cell touch with a fibroblast is disclosed. Moreover, a production method of a smooth muscle implant which includes: the culturing step S4 that cultures by a condition that makes a mesenchymal stem cell touch with a fibroblast; and a recovery step S5 that collects the smooth muscle cell that is differentiated from a mesenchymal stem cell by the culturing step S4 is disclosed. Moreover, a smooth muscle implant produced by the production method of the smooth muscle implant is disclosed.