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A steerable smart catheter tip realized by flexible hydrogel actuator

机译:由柔性水凝胶致动器实现的可操纵的智能导管尖端

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This paper reports the first smart catheter tip realized by integrating a thermoresponsive hydrogel on a flexible strip of microfabricated heater, targeting at applications in minimally invasive vascular treatments and other surgical procedures. A bimorph-like active tip structure is fabricated by integrating a 500-μm-thick layer of poly(N-isopropylacrylamide) hydrogel on top of the 20-mm-long region of a 3.5-mm-wide flexible polyimide strip that embeds a micropatterned resistive heater. The activation of the heater stimulates the hydrogel layer to shrink and bend the flexible tip, providing the catheter with controlled steering ability for a wide range of navigation angles. Infrared imaging shows uniform heating over the entire hydrogel region within a ~2-°C variation. The fabricated prototypes are assembled on commercial catheter tubes and operated to demonstrate bending angles of up to 130°, which is significantly larger compared with other active catheters reported. Dynamic characterization of the device also shows promising results towards the target application.
机译:本文报道了第一智能导管尖端通过将热响应水凝胶整合在柔性的微制加热器上,靶向在微创血管处理和其他外科手术中的应用。通过将500μm厚的聚(n-异丙基丙烯酰胺)水凝胶上整合在3.5毫米宽的柔性聚酰亚胺条的顶部的顶部,通过将500μm厚的聚(n-异丙基丙烯酰胺)水凝胶层集成在3.5毫米宽的柔性聚酰亚胺条的顶部的顶部制造。嵌入微图案电阻加热器。加热器的激活刺激水凝胶层以收缩和弯曲柔性尖端,从而为导管提供有控制的转向能力,用于广泛的导航角度。红外成像显示在〜2℃的整个水凝胶区域上均匀加热。制造的原型在商用导管管上组装,并操作以证明弯曲角度高达130°,与报告的其他有源导管相比显着更大。该装置的动态表征还显示了对目标应用的有希望的结果。

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