An in vivo MEMS sensor system for percutaneous measurement of urinary bladder

摘要

An in vivo sensor system for direct measurement of pressure in the human urinary bladder is developed. The core component in the system is a small-sized and highly sensitive piezoresistive MEMS pressure sensor element integrated in a sensor catheter. The sensor catheter is wired to an external module for biasing, sampling, conversion and storage of sensor measurements. Our solution provides a target sensor placed directly into the urinary bladder and a reference sensor placed outside the bladder wall through a suprapubic and minimally invasive technique. Physiological recordings through natural filling and emptying cycles of the bladder are achievable. The case report from the first 17-hours investigation in a patient is presented in this paper. It reveals that the procedure was successful and no complications occurred. The patient expressed good experience during the participation. A functionality test shows that the percutaneous pressure sensor system responds immediately to external pressure stimuli.