3D Graphene Oxide Scaffolds as Pro-Regenerative Biomaterials in the Rat Injured Spinal Cord

摘要

In the absence of any additional drug-loading or functionalization, 3D rGO scaffolds are able to mediate neural repair at the injured spinal cord by permitting neurites to grow through the lesion site assisted by functional blood microvessels. Moreover, these foams stabilize the damage by decreasing perilesional areas of gliosis. This compilation of positive effects might eventually drive to neural repair and functional recovery after SCI. Future studies will deepen on longer times of implantation, with focus on tracing techniques to identify the origin of the neurites growing inside the foams.