EFFECTS OF SPORODERM-BROKEN GERMINATION ACTIVATED GANODERMA SPORES ON TREATMENT OF SPINAL CORD INJURY AND PROLIFERATION AND/OR DIFFERENTIATION OF NEURAL STEM CELLS IN INJURED SPINAL CORD

摘要

The present invention provides a method for preventing and reducing embryonic neural tube defects (NTDs) caused by cell cycle arrest in the neuroepithelial cells of the embryo. The method comprises administering germination activated sporoderm-broken Ganoderma lucidum spores ("GLSs") to a female mammal capable of becoming pregnant an effect amount of GLSs. GLSs are preferred to be administered to the female mammal prior to or at an early stage of the pregnancy. The GLSs reduce embryonic NTDs caused by cell cycle arrest in the neuroepithelial cells.