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Biocompatible encapsulation and interconnection technology for implantable electronic devices

机译:用于植入式电子设备的生物相容性封装和互连技术

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A biocompatible packaging process for implantable electronic systems is under development at imec, combiningbiocompatibility, hermeticity, extreme miniaturization and cost aspects.In a first phase of this packaging sequence, hermetic chip sealing is performed by encapsulating all chips to realizea bi-directional diffusion barrier preventing body fluids to leach into the package causing corrosion, and preventingIC materials such as Cu to diffuse into the body, causing various adverse effects. For cost effectiveness, this chipsealing is performed as post-processing at wafer level, using modifications of standard clean room (CR) fabricationtechniques. Well known conductive and insulating CR materials are investigated with respect to theirbiocompatibility, biostability, diffusion barrier properties and sensitivity to corrosion. Material selection andintegration aspects are modified until good properties are obtained.In a second phase of the packaging process, all chips of the final device should be electrically connected, applying abiocompatible metallization scheme. We selected the use of Pt due to its excellent biocompatibility and corrosionresistance. Since Pt is very expensive, a cost effective Pt-selective plating process is developed.During the third packaging step, all system components such as electronics, passives, a battery,... will beinterconnected. To provide sufficient mechanical support, all components are finally embedded using a medicalgrade elastomer such as PDMS or Poly-urethane.
机译:imec正在开发一种适用于植入式电子系统的生物相容性包装工艺,该工艺结合了 生物相容性,气密性,极端小型化和成本方面。 在此封装顺序的第一阶段,通过封装所有芯片以实现密封芯片密封 双向扩散屏障,可防止体液浸入包装中导致腐蚀,并防止 诸如Cu之类的IC材料会扩散到体内,引起各种不良影响。为了节省成本,该芯片 通过修改标准洁净室(CR)的制造工艺,在晶圆级进行密封处理,作为后处理 技术。对众所周知的导电和绝缘CR材料进行了研究 生物相容性,生物稳定性,扩散阻隔性能和对腐蚀的敏感性。材料选择和 修改集成方面,直到获得良好的性能。 在封装过程的第二阶段,应将最终设备的所有芯片电连接,并施加一个 生物相容性金属化方案。我们选择使用Pt是因为它具有出色的生物相容性和耐腐蚀性能 反抗。由于Pt非常昂贵,因此开发了具有成本效益的Pt选择性电镀工艺。 在第三包装步骤中,所有系统组件(例如电子设备,无源元件,电池等)都将处于 互联。为了提供足够的机械支持,所有组件最终都使用医疗设备嵌入 等级的弹性体,例如PDMS或聚氨酯。

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