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Progress towards Incorporation of Antimicrobial Peptides for Disease Resistance in Citrus

机译:在柑橘中掺入抗菌肽抗菌肽的进展

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Antimicrobial peptides play important roles in the innate immune response and can be found to occur in all classes of life, including humans. These peptides are usually small proteins and have an ability to associate with bacterial cell membranes. Antimicrobial peptides are also characterized by their broad spectrum antibiotic property. Citrus canker and Huanglongbing (HLB) are the two major diseases threatening the global citrus industry. All commercial grapefruit, sweet orange and tangerine cultivars are susceptible to these diseases, and it is difficult to create tolerant cultivars via conventional breeding. Incorporation of one or more genes encoding for antimicrobial peptides into the citrus genome via genetic engineering could potentially result in development of cultivars resistant to these diseases, without modifying the varietal fidelity.
机译:抗微生物肽在先天免疫反应中起重要作用,并且可以在包括人类在内的所有生命中发现。这些肽通常是小蛋白质并且具有与细菌细胞膜相关的能力。抗微生物肽的特征在于它们的广谱抗生素特征。柑橘溃疡和黄龙兵(HLB)是威胁全球柑橘行业的两种主要疾病。所有商业葡萄柚,甜橙和橘子品种易受这些疾病的影响,并且难以通过常规育种产生耐受性品种。通过基因工程将用于抗微生物肽的一种或多种基因的掺入到柑橘基因组中可能导致耐种这些疾病的品种的发展,而不会改变品种保真度。

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